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Title:
GINGIVA CARE AGENT AND GINGIVA CARE ORAL COMPOSITION CONTAINING THE SAME
Document Type and Number:
Japanese Patent JP2018020994
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide methods which enhance the gingiva by inhibiting intercellular adhesion failure due to the decreased expression of intercellular adhesion factor by proinflammatory cytokine caused by physical or chemical stimulations to inhibit gingival regression or the formation of a periodontal pocket.SOLUTION: A composition containing at least one selected from the group consisting of glycyrrhizinic acid or a pharmaceutically acceptable salt thereof, sodium copper chlorophyllin, and triclosan is used as a gingiva care agent (an agent for inhibiting reduction in intercellular adhesion factor expression, an agent for inhibiting failure in gingival epithelial cell adhesion, a gingival recession inhibitor, a periodontal pocket formation inhibitor, or a gingiva enhancer), or as a gingiva care oral composition.SELECTED DRAWING: None

Inventors:
KURAMITSU SHOHEI
ZHENG MEIXIAO
Application Number:
JP2016155029A
Publication Date:
February 08, 2018
Filing Date:
August 05, 2016
Export Citation:
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Assignee:
KOBAYASHI PHARMACEUTICAL CO LTD
International Classes:
A61K8/63; A61K8/34; A61K8/58; A61K31/085; A61K31/409; A61K31/704; A61P1/02; A61P43/00; A61Q11/00
Domestic Patent References:
JP2003532664A2003-11-05
JP2017095382A2017-06-01
JP2004083443A2004-03-18
JP2002068971A2002-03-08
JP2009107988A2009-05-21
JP2011073997A2011-04-14
JP2011126818A2011-06-30
JP2009184936A2009-08-20
JPH0840858A1996-02-13
JP2002068791A2002-03-08
JPH05194203A1993-08-03
Foreign References:
WO2016104524A12016-06-30
KR20080063731A2008-07-07
KR20090121752A2009-11-26
KR20160007049A2016-01-20
Other References:
池田克巳ほか: "殺菌剤および抗炎症剤配合液状歯磨剤の歯周病予防効果に関する研究", 日本歯周病学会会誌, vol. 第36巻、第1号, JPN6021000512, 1994, ISSN: 0004587273
SUNSTAR, JAPAN: "Medicated Dental Mouthwash", MINTEL GNPD [ONLINE], JPN6021034679, October 2012 (2012-10-01), ISSN: 0004587274
Attorney, Agent or Firm:
Patent Business Corporation Saegusa International Patent Office