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Title:
【発明の名称】抗ウイルス剤としての修飾ベンズイミダゾールヌクレオシド
Document Type and Number:
Japanese Patent JP2001501580
Kind Code:
A
Abstract:
This invention pertains to nucleoside analogs that have antiviral activity and improved metabolic stability, compositions comprising them, and methods of antiviral treatment employing them. More particularly, this invention pertains to imidazo[1,2-a]pyridine C-nucleosides, as exemplified by compounds such as imidazo[l,2-a]pyridine C5-nucleosides and imidazo[1,2-a]pyridine C3-nucleosides, and may be represented by formula (I), wherein exactly one of Q3 and Q5 is a sugar-like moiety; exactly one of Q3 and Q5 is -H; and Q2, Q6, Q7 and Q8 are independently imidazo[1,2-a]pyridine substituents, such as -H, -F, -Cl, -Br and -I.

Inventors:
Townsend, Leroy Bee.
Drak, John Sea.
Freeman, George A.
Application Number:
JP52691997A
Publication Date:
February 06, 2001
Filing Date:
January 22, 1997
Export Citation:
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Assignee:
The Regents of the University of Michigan
GLAXO GROUP LIMITED
International Classes:
A61K31/7056; A61P31/12; C07D471/04; C07H7/06; C07H9/04; C07H11/00; C07H19/052; (IPC1-7): C07H19/052; A61K31/7056; A61P31/12
Attorney, Agent or Firm:
Shusaku Yamamoto