Title:
A painkiller compound, a method, and a tablet
Document Type and Number:
Japanese Patent JP6002153
Kind Code:
B2
Abstract:
Provided are analgesic compounds, and salts thereof, of formula: (I) wherein A is: (A) Additionally, pharmaceutical formulations and methods of use employing the above compounds are provided.
Inventors:
Defoie, Jean Marie
Holmstrom, Scott Dale
Chen, Shuhui
Chang, Yang
Wu, Wentao
Pen, cien
Ma, Eugen
Lu, Run
Holmstrom, Scott Dale
Chen, Shuhui
Chang, Yang
Wu, Wentao
Pen, cien
Ma, Eugen
Lu, Run
Application Number:
JP2013551992A
Publication Date:
October 05, 2016
Filing Date:
January 13, 2012
Export Citation:
Assignee:
Eli Lilly and Company
International Classes:
C07C217/24; A61K31/135; A61K45/00; A61P25/04; C07C215/64; C07C219/28
Domestic Patent References:
| JP10338665A |
Other References:
DEUTSCH, H. M. et al.,Synthesis and pharmacology of site-specific cocaine abuse treatment agents: 2-(aminomethyl)-3-phenylbicyclo[2.2.2]- and -[2.2.1]alkane dopamine uptake inhibitors,Journal of Medicinal Chemistry,1999年,42(5),p.882-895
Bridged compounds as potential analgetics. Substituted 3-exo-dimethylaminomethylnorbornanes as potential analgetics. Syntheses and stereochemistry of some 2-hydroxy-2-aryl substituted 3-exo-dimethylaminomethylnorbornanes,BECKETT, A. H. et al.,Journal of Medicinal Chemistry,1972年,15(6),p.593-594
Synthesis of exo-3-phenylbicyclo[3.2.1]oct-3-en-2-amine and related compounds as potential analgesics,HARRIS, A. et al.,Journal of Medicinal Chemistry,1983年,26(1),p.55-60
Bridged compounds as potential analgetics. Substituted 3-exo-dimethylaminomethylnorbornanes as potential analgetics. Syntheses and stereochemistry of some 2-hydroxy-2-aryl substituted 3-exo-dimethylaminomethylnorbornanes,BECKETT, A. H. et al.,Journal of Medicinal Chemistry,1972年,15(6),p.593-594
Synthesis of exo-3-phenylbicyclo[3.2.1]oct-3-en-2-amine and related compounds as potential analgesics,HARRIS, A. et al.,Journal of Medicinal Chemistry,1983年,26(1),p.55-60
Attorney, Agent or Firm:
Hiroshi Kobayashi
Norio Omori
Yasuhito Suzuki
Norio Omori
Yasuhito Suzuki