Title:
A percutaneous absorption tablet containing Donepezil , and a manufacturing method for the same
Document Type and Number:
Japanese Patent JP6132407
Kind Code:
B2
Abstract:
The present invention provides a transdermal delivery system (for example, in the form of a patch) having a double-layer structure including a drug-containing matrix layer and an adhesive layer, wherein the drug-containing matrix layer is obtained by completely dissolving donepezil using a certain polymer and then formulating along with an adhesive; and a process for preparing the same. The transdermal delivery system according to the present invention does not show any crystallization of donepezil in the formulation, can release donepezil at a uniform rate for a long time, and can inhibit the release dumping phenomenon that occurs in a transdermal delivery system having a single-layer structure.
Inventors:
Im, john soup
Fan, Yong Yun
Yun, Wonno
Park, Yojin
Kim, hemin
Oh, Junkyo
Kim, fun tech
Lee, Bong Young
Fan, Yong Yun
Yun, Wonno
Park, Yojin
Kim, hemin
Oh, Junkyo
Kim, fun tech
Lee, Bong Young
Application Number:
JP2014559823A
Publication Date:
May 24, 2017
Filing Date:
February 26, 2013
Export Citation:
Assignee:
SK CHEMICALS CO.,LTD.
International Classes:
A61K31/445; A61K9/70; A61K47/32; A61K47/34; A61P25/28
Domestic Patent References:
| JP63307814A | ||||
| JP1104008A | ||||
| JP10072343A | ||||
| JP61246122A |
Foreign References:
| CN102188363A |
Attorney, Agent or Firm:
Ryu Iwatani