Title:
良好な水溶解性を有する作用物質のための作用物質の制御送達を有する医薬組成物
Document Type and Number:
Japanese Patent JP5661281
Kind Code:
B2
Abstract:
A pharmaceutical preparation comprising: a) a core with an active ingredient and with an organic acid and/or the salt of an organic acid; and b) a coating which envelops the core and which comprises a polymer content of (meth)acrylate copolymers which have not more than 15% by weight of cationic or anionic groups, and which comprises at least 60% by weight of a (meth)acrylate copolymer which is composed of free-radically polymerized units of 93 to 98% by weight C1- to C4-alkyl esters of acrylic or of methacrylic acid and 7 to 2% by weight (meth)acrylate monomers having a quaternary ammonium group in the alkyl radical, wherein the active ingredient has a solubility in water of at least 10 g/l at 20° C. and the coating comprises silicon dioxide particles having an average particle size in the range from 1 to 50 mum.
Inventors:
ハンス−ウルリヒ ペーテライト
ヘマ ラヴィシャンカール
シャラッダ ボディンゲ
ヘマ ラヴィシャンカール
シャラッダ ボディンゲ
Application Number:
JP2009524903A
Publication Date:
January 28, 2015
Filing Date:
September 21, 2006
Export Citation:
Assignee:
エボニック レーム ゲゼルシャフト ミット ベシュレンクテル ハフツングＥｖｏｎｉｋ Ｒｏｅｈｍ ＧｍｂＨ
International Classes:
A61K31/135; A61K9/32; A61K31/137; A61K31/522; A61K47/02; A61K47/12; A61K47/32
Attorney, Agent or Firm:
アインゼル Felix-Reinhardt
Takuya Kuno
篠 Ryoichi
Takuya Kuno
篠 Ryoichi
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