Title:
新規ピリミジン誘導体およびこれを活性成分として含む薬学的組成物
Document Type and Number:
Japanese Patent JP2014521638
Kind Code:
A
Abstract:
The present invention relates to a compound represented by formula (I) for inhibiting the activity of diacylglycerol O-acyltransferase type 1 (DGAT1), and pharmaceutically acceptable salts thereof, and a pharmaceutical composition comprising same as an active ingredient. The compound of the present invention may be used effectively in the treatment or prevention of a disease or condition mediated by the activity of DGAT1 such as obesity, type II diabetes, dyslipidemia, metabolic syndrome, and the like, without any adverse effects:
wherein A, B, X, and R 5 to R 7 are the same as defined in the specification.
Inventors:
Park チョルヒョン
Kim Burdock jeon
John ヨンヒ
Kim ナムドゥ
Chang ヨンキル
Kim ミンソプ
Kim Burdock jeon
John ヨンヒ
Kim ナムドゥ
Chang ヨンキル
Kim ミンソプ
Application Number:
JP2014522734A
Publication Date:
August 28, 2014
Filing Date:
June 29, 2012
Export Citation:
Assignee:
ハンミ Firm. CO. and LTD.
International Classes:
C07D487/04; A61K31/519; A61K31/5377; A61P1/16; A61P3/02; A61P3/04; A61P3/10; A61P9/10; A61P9/12; A61P11/00; A61P15/00; A61P19/02; A61P19/06; A61P27/12; A61P43/00; C07D495/04; C07B61/00
Attorney, Agent or Firm:
Katsumori Iseki