Title:
GRAFT WITH BIOLOGICAL ACTIVITY AND COMPOSITE
Document Type and Number:
Japanese Patent JP2016154880
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide a graft with various biological activities for allogenic transplantation, autologous transplantation or heterogenic transplantation in bone grafting and/or biocompatible material and a manufacturing method of the material.SOLUTION: A bone material is collected from donors, the collected material is exposed to a solvent having a constitution for releasing growth factor and biological active material from a cell material of the collected bone material and then the collected bone material is washed with a washing agent and pH of the collected material is practically neutralized and antibacterial polysaccharide is contained. An implant is an implant for orthopedic surgery which may contain a bone stimulant. There is provided the implant for orthopedic surgery containing decalcified bone holding BMP-2, deacetylated chitosan with concentration of less than 2.5% in a range of 50 to 99%, the bone stimulant and water. There is provided an implant where the bone stimulant is preferably calcium salt with concentration of more than 10%, more preferably 40% or more.SELECTED DRAWING: None
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Inventors:
GOVIL AMIT PRAKASH
CHRISTIAN GAMBOA
CHRISTIAN GAMBOA
Application Number:
JP2016077958A
Publication Date:
September 01, 2016
Filing Date:
April 08, 2016
Export Citation:
Assignee:
GOVIL AMIT PRAKASH
International Classes:
A61L27/00
Other References:
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ＪＯＵＲＮＡＬ ＯＦ ＢＩＯＭＥＤＩＣＡＬ ＭＡＴＥＲＩＡＬＳ ＲＥＳＥＡＲＣＨ． ＰＡＲＴ Ａ．, vol. Ｖｏｌ．８６，Ｎｏ．３, JPN6015040034, 2008, pages ｐ８２４−８３２
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Attorney, Agent or Firm:
Mitsuhiko Watanabe