Title:
ポリマータンパク質微粒子
Document Type and Number:
Japanese Patent JP7217247
Kind Code:
B2
Abstract:
The present invention relates to microparticles comprising a protein particle core coated with a biodegradable polymer cortex, methods of manufacturing such microparticles, and methods for modulating the release of a protein.The microparticles are used in extended release pharmaceutical formulations for use in the vitreous for the treatment of vascular eye disorders.
Inventors:
Chen Hunter
Walsh Scott
Walsh Scott
Application Number:
JP2020112359A
Publication Date:
February 02, 2023
Filing Date:
June 30, 2020
Export Citation:
Assignee:
REGENERON PHARMACEUTICALS, INC.
International Classes:
A61K38/17; A61K9/14; A61K9/50; A61K38/22; A61K39/395; A61K47/34; A61K47/38; A61K47/64; A61K47/68; A61P27/02; A61P43/00; C07K14/705; C07K16/18; C07K17/02; C07K17/12; C07K19/00
Domestic Patent References:
JP2010522743A |
Other References:
Journal of Pharmacology and Experimental Therapeut,1997年,Vol.281,No.3,p1431-1439
Toxicological Sciences,1999年,Vol.52,No.1,p101-106
Nature Medicine,1996年,Vol.2,No.7,p795-799
Molecular Vision,2005年,Vol.11,p1002-1011
European Journal of Pharmaceutics and Biopharmaceu,2004年,Vol.57,No.2,p207-212
Journal of Ocular Pharmacology and Therapeutics,2011年06月,Vol.27,No.3,p219-224
Ophthalmology,2011年06月,Vol.118,No.6,p1098-1106
Ophthalmology,2011年09月,Vol.118,No.9,p1819-1826
Toxicological Sciences,1999年,Vol.52,No.1,p101-106
Nature Medicine,1996年,Vol.2,No.7,p795-799
Molecular Vision,2005年,Vol.11,p1002-1011
European Journal of Pharmaceutics and Biopharmaceu,2004年,Vol.57,No.2,p207-212
Journal of Ocular Pharmacology and Therapeutics,2011年06月,Vol.27,No.3,p219-224
Ophthalmology,2011年06月,Vol.118,No.6,p1098-1106
Ophthalmology,2011年09月,Vol.118,No.9,p1819-1826
Attorney, Agent or Firm:
Shimizu Hatsushi
Masao Haruna
Hirotaka Yamaguchi
Shun Jinbe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Hideki Kodera
Masato Ozeki
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Shun Jinbe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Hideki Kodera
Masato Ozeki
Kazuya Kawamoto
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