Title:
The polynucleotides which code a MHC class I restriction hTERT epitope, those similar objects, or the poly epitope
Document Type and Number:
Japanese Patent JP6257667
Kind Code:
B2
Abstract:
This invention relates to the field of anticancer therapy, and to the identification of immunogenic peptides derived from the human telomerase reverse transcriptase (hTERT). The present invention relates to polynucleotides encoding hTERT epitopes restricted to MHC class I molecule, analogues thereof and polyepitopes containing such epitopes and/or analogues. Are also included in the present invention, vector and cell comprising such polynucleotides. The present invention also concerns composition comprising hTERT polypeptides, corresponding polynucleotides, vectors and cells, for use in the treatment and/or prevention of cancer.
Inventors:
Pierre Langrad-Do-Moyan
Francisco Garcia Pon
Olivier Adtevi
Sylvain Cardino
Christine Neuve
Francisco Garcia Pon
Olivier Adtevi
Sylvain Cardino
Christine Neuve
Application Number:
JP2016029927A
Publication Date:
January 10, 2018
Filing Date:
February 19, 2016
Export Citation:
Assignee:
INSTITUT PASTEUR
Anstituto Nacional de la Sante et de la Le Chalche Medical (Inselm)
Anstituto Nacional de la Sante et de la Le Chalche Medical (Inselm)
International Classes:
C12N15/09; A61K31/7088; A61K38/45; A61K39/00; A61P35/00; C12N5/07; C12N5/0783; C12N5/0784; C12N5/09; C12N5/10; C12N9/12
Domestic Patent References:
| JP2002520293A | ||||
| JP2001081042A | ||||
| JP2002509716A | ||||
| JP2002514928A |
Other References:
Science,1997年 4月25日,Vol.276, No.5312,pp.561-567
Attorney, Agent or Firm:
Yasuhiko Murayama
Shinya Mitsuhiro
Shinya Mitsuhiro