Title:
アミドアセトニトリル化合物のラセミ体からのアミドアセトニトリル化合物の鏡像異性体の調製方法
Document Type and Number:
Japanese Patent JP5112074
Kind Code:
B2
Abstract:
The invention is directed at a new process for the preparation of pure enantiomers from the racemate of amidoacetonitrile compounds of formula wherein R1, R2 and R3, independently of each other, signify hydrogen, halogen, nitro, cyano, C1-C6-alkyl, halogen-C1-C6-alkyl, C1-C6-alkoxy, halogen-C1-C6-alkoxy, C2-C6-alkenyl, halogen-C2-C6-alkenyl, C2-C6-alkinyl, halogen-C2-C6-alkinyl, C2-C6-alkenyloxy, halogen-C2-C6-alkenyloxy, C1-C6-alkylthio, halogen-C1-C6-alkylthio, C1-C6-alkylsulfonyloxy, halogen-C1-C6-alkylsulfonyloxy, C1-C6-alkylsulfinyl, halogen-C1-C6-alkylsulfinyl, C1-C6-alkylsulfonyl, halogen-C1-C6-alkylsulfonyl, C1-C6-alkenylthio, halogen-C1-C6-alkenylthio, C1-C6-alkenylsulfinyl, halogen-C1-C6-alkenylsulfinyl, C1-C6-alkenylsulfonyl, halogen-C1-C6-alkenylsulfonyl, C1-C6-alkylamino, di-(C1-C6-alkyl)amino, C1-C6-alkylaminocarbonyl, di-(C1-C6-alkyl)aminocarbonyl, C1-C6-alkylsulfonylamino, halogen-C1-C6-alkylsulfonylamino, C1-C6-alkylcarbonyl, halogen-C1-C6-alkylcarbonyl, C1-C6-alkoxycarbonyl, unsubstituted or one- to five-fold substituted phenyl, unsubstituted or one- to five-fold substituted phenoxy, unsubstituted or one- to five-fold substituted phenylacetylenyl, unsubstituted or one- to four-fold substituted pyridyloxy, unsubstituted or one- to four-fold substituted pyridyl or unsubstituted or one- to seven-fold substituted naphthyl, the substituents in each case being selected from the group consisting of halogen, nitro, cyano, C1-C6-alkyl, halogen-C1-C6-alkyl, C1-C6-alkoxy and halogen-C1-C6-alkoxy, which are useful in the control of endo- and ectoparasites in and on warm-blooded animals, especially productive livestock and domestic animals, as well as on plants.
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Inventors:
Dou Cray, Pierre
Gobli, Noel
Goebel, Thomas
Francois, Potoura
Gobli, Noel
Goebel, Thomas
Francois, Potoura
Application Number:
JP2007539546A
Publication Date:
January 09, 2013
Filing Date:
November 07, 2005
Export Citation:
Assignee:
Novartis Age
International Classes:
C07C315/06; A01N37/10; A01P7/00; C07C317/14; C07B57/00
Domestic Patent References:
| JP2004521097A | ||||
| JP2000026392A | ||||
| JP5215736A | ||||
| JP2138237A | ||||
| JP2007510632A | ||||
| JP2007513911A |
Foreign References:
| WO2004000793A1 | ||||
| US3401178 |
Other References:
社団法人 日本化学会編,光学異性体の分離〔季刊 化学総説 No.6〕,1999年 6月10日,2-14,132-143頁
Attorney, Agent or Firm:
Yoshio Kawaguchi
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura