Title:
非環式HCVプロテアーゼインヒビターの調製方法
Document Type and Number:
Japanese Patent JP5156374
Kind Code:
B2
Abstract:
Disclosed are highly convergent processes for preparing compounds of formula (I), which compounds are potent active agents for the treatment of hepatitis C virus (HCV) infection: The disclosed processes use SNAr-type coupling reactions between peptidic compounds having a hydroxyproline moiety of the following formula: and halogenated or sulfonated bromoquinoline compounds.
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Inventors:
Bussakka Karl Alan
Furtos Rogelio Perez
Haddad Niza
Kapadia Thresh Earl
Lorenz John Charles
Saha Anjan
Senana Yake Chris Hugh
Way Shudon
Furtos Rogelio Perez
Haddad Niza
Kapadia Thresh Earl
Lorenz John Charles
Saha Anjan
Senana Yake Chris Hugh
Way Shudon
Application Number:
JP2007515258A
Publication Date:
March 06, 2013
Filing Date:
May 23, 2005
Export Citation:
Assignee:
Boehringer Ingelheim International GmbH
International Classes:
C07K5/083; A61K31/4709; C07C217/84; C07C225/22; C07D277/56; C07D417/04; C07D417/14; C07K5/08; A61K38/00; A61P1/16; A61P31/14; C07K5/087
Domestic Patent References:
JP2006528937A |
Foreign References:
WO2000009543A1 |
Attorney, Agent or Firm:
Sadao Kumakura
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Koji Hirayama
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Koji Hirayama