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Title:
鏡像異性的に富化した環式β-アリール又はヘテロアリールカルボン酸の調製方法
Document Type and Number:
Japanese Patent JP2009532410
Kind Code:
A
Abstract:
The present invention relates to a process for the preparation of cis substituted cyclic beta-aryl or heteroaryl carboxylic acid derivatives in high diastereo- and enantioselectivity by enantioselective hydrogenation in accordance with the following scheme wherein X, Ar, n, and m are defined herein and corresponding salts thereof.

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Inventors:
Bachmann, Stephan
Scallone, michelangelo
Schneider, Patrick
Application Number:
JP2009503527A
Publication Date:
September 10, 2009
Filing Date:
March 26, 2007
Export Citation:
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Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
C07C51/36; C07C61/39; C07D207/16; C07D211/60; C07D333/38; C07D401/04; C07B53/00; C07B61/00
Domestic Patent References:
JPH0873400A1996-03-19
Foreign References:
US5721251A1998-02-24
US5804578A1998-09-08
WO2005068427A12005-07-28
Attorney, Agent or Firm:
Hajime Tsukuni
Koshiro Tsukuda
Fusayuki Saito



 
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