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Title:
バルサルタンの調製方法
Document Type and Number:
Japanese Patent JP2009504800
Kind Code:
A
Abstract:
The invention relates to novel compound of formula (IV), which is an organic acid salt of N-[(2′-cyanobiphenyl-4-yl)methyl]-(L)-valine ester. This compound is an useful intermediate for process of preparation of Valsartan of formula (I), chemically known as (S)-N-(1-Carboxy-2-methylprop-1-yl)-N-pentanoyl-N-[2′-(1H-terazol-5-yl)biphenyl-4-ylmethyl]amine. This invention also relates to a process for preparing Valsartan using novel intermediate of formula (IV).

Inventors:
Soniro Hit Ravikant
Basoya Sanjay Rakhavai
Gotica Ravindra Chardetta
Pandy Anand Kumar
Shahhetar Remesh Chandra
Application Number:
JP2008527597A
Publication Date:
February 05, 2009
Filing Date:
June 29, 2006
Export Citation:
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Assignee:
Alembic Limited
International Classes:
C07C255/58; C07C55/06; C07C253/30; C07D257/04; C07B53/00; C07B61/00
Domestic Patent References:
JPH04235149A1992-08-24
JPH11322697A1999-11-24
Foreign References:
WO2005049588A12005-06-02
Attorney, Agent or Firm:
Nagoya International Patent Service Corporation