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Title:
A pro caspase combined therapy for Glioblastoma
Document Type and Number:
Japanese Patent JP6222608
Kind Code:
B2
Abstract:
The invention provides compositions and methods for the induction of cell death, for example, cancer cell death. Combinations of compounds and related methods of use are disclosed, including the use of compounds in therapy for the treatment of cancer and selective induction of apoptosis in cells. The disclosed drug combinations can have lower neurotoxicity effects than other compounds and combinations of compounds.

Inventors:
Hagen Rosa, Paul Jay.
Botham, Rachel Sea.
Fan, Timothy M.
Gilbert, Mark Jay.
Handley, Michael K.
Joshi, Avad Hut
Riggins, Gregory Jay.
Thalasso, Theodore M.
Application Number:
JP2014561081A
Publication Date:
November 01, 2017
Filing Date:
March 06, 2013
Export Citation:
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Assignee:
The Board of Trustees of the University of Illinois
VANQUISH ONCOLOGY,INC.
The Johns Hopkins University
International Classes:
A61K31/495; A61K9/08; A61K9/20; A61K9/48; A61K31/4188; A61K47/40; A61P35/00; A61P43/00
Domestic Patent References:
JP2008545718A
Other References:
日本癌学会学術総会記事,2008年 9月30日,67,242
改訂 医薬品添加物ハンドブック Handbook of PHARMACEUTICAL EXCIPIENTS,株式会社薬事日報社,2007年 2月28日,Fifth Edition,400-406,ISBN:978-4-8408-0968-9
Attorney, Agent or Firm:
Ikeda adult
Junichiro Sakamaki
Masakazu Noda
Kazuhiro Yamaguchi