Title:
プロドラッグである5-アミノ-3-(3’-デオキシ-β-D-リボフラノシル)-チアゾロ[4,5-d]ピリミジン-2,7-ジオン
Document Type and Number:
Japanese Patent JP5345527
Kind Code:
B2
Abstract:
The invention is directed to 5-amino-3-(3′-deoxy-β-D-ribofuranosyl)-thiazolo[4,5-d]pyrimidin-2,7-dione prodrugs, whose metabolized parent compound has immunomodulatory activity. The invention also relates to the therapeutic use of such prodrugs and pharmaceutical compositions thereof in treating disease states associated with abnormal cell growth, such as cancer.
Inventors:
Hailey, Gregory, Jay.
Lennox, Joseph, Earl.
Cyan, Alan, Shin
Webber, Stefan, Yi.
Lennox, Joseph, Earl.
Cyan, Alan, Shin
Webber, Stefan, Yi.
Application Number:
JP2009516736A
Publication Date:
November 20, 2013
Filing Date:
June 21, 2007
Export Citation:
Assignee:
Anadis Pharmaceuticals, Inc.
International Classes:
C07D513/04; A61K31/519; A61P9/10; A61P13/08; A61P17/06; A61P31/00; A61P35/00; A61P35/02; A61P37/04; A61P43/00
Domestic Patent References:
| JP3504122A | ||||
| JP2005515196A |
Attorney, Agent or Firm:
Atomi International Patent Office
Previous Patent: JPS5345526
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