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Title:
3-置換-3’-ヒドロキシプロピオニトリルの製造方法
Document Type and Number:
Japanese Patent JP4550107
Kind Code:
B2
Abstract:
The present invention relates to a method for the preparation of 3-substituted-3'-hydroxypropionitrile, more particularly, to a method for the preparation of 3-substituted-3'-hydroxypropionitrile which comprises performing ring opening of 1-substituted-ethylene oxide using sodium cyanide and citric acid in a range of pH 7.8~8.3 to provide 3-substituted-3'-hydroxypropionitrile in high optical purity and with high yield.

Inventors:
Son, Jeon Ho
Yun, Jin-won
Lee, Hotheon
Kim, Ho-cheol
Kim, Seong-jin
Application Number:
JP2007502693A
Publication Date:
September 22, 2010
Filing Date:
March 13, 2004
Export Citation:
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Assignee:
Arestec corporation
International Classes:
C07C253/16; C07C253/00; C07C255/16; C07C255/17; C07C255/19; C07B53/00; C07C255/12; C07C255/13; C07C255/15; C07C255/20; C07C255/31; C07C255/36
Domestic Patent References:
JP2000063321A
JP5310671A
JP5092946A
JP63316758A
Attorney, Agent or Firm:
Mikio Hatta
Yasuo Nara
Katsuyuki Utani
Ken Fujita
Masanori
Toshihiro Hasegawa