Title:
【発明の名称】ブデソニドの製造方法
Document Type and Number:
Japanese Patent JP2965352
Kind Code:
B2
Abstract:
The present invention relates to a novel process for the manufacture of (22 R,S)-16 alpha , 17 alpha -butylidenedioxy-11 beta , 21-dihydroxypregna-1,4-diene-3,20 dione (I) by reacting 11 beta , 16 alpha , 17 alpha 21-tetrahydroxypregna-1,4-diene (II) with butanal, CH3-CH2-CH2-CHO, in acetonitrile in presence of p-toluenesulphonic acid as a catalyst.
Inventors:
HOFUSUTORAATO ROOBERUTO HERITSUTO
RAEIMAKERUSU PETORUSU HENDORIKUSU
FUREEIHOFU PIITERU
RAEIMAKERUSU PETORUSU HENDORIKUSU
FUREEIHOFU PIITERU
Application Number:
JP51416190A
Publication Date:
October 18, 1999
Filing Date:
September 27, 1990
Export Citation:
Assignee:
ASUTORA AB
International Classes:
C07J5/00; C07J71/00; C07J75/00; (IPC1-7): C07J71/00; C07J75/00
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)