Title:
エチル-N-(2,3-ジクロロ-6-ニトロベンジル)グリシンの製造方法
Document Type and Number:
Japanese Patent JP4275748
Kind Code:
B2
Abstract:
The known blood platelet reducing agent Anagrelide is prepared via an improved process starting with commercially available 2,3-dichliorotoluene and involving novel intermediates represented by the formulas: wherein Y is Br, Cl or I. Compound (G) is reacted with ethyl glycine to form the well-known intermediate ethyl-N-(2,3-dichloro-6-nitro benzyl) glycine which is then used following conventional process steps to form Anagrelide.
Inventors:
Philip Sea Lang
Application Number:
JP6307196A
Publication Date:
June 10, 2009
Filing Date:
March 19, 1996
Export Citation:
Assignee:
Shire LRC
International Classes:
C07D487/04; C07C201/08; C07C205/12; C07C227/14; C07C227/18; C07C229/36; C07D235/00; C07D339/00
Domestic Patent References:
| JP4046140A | ||||
| JP2004719A | ||||
| JP2221233A | ||||
| JP48086894A |
Attorney, Agent or Firm:
Shinjiro Ono
Kazuo Shamoto
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Kazuo Shamoto
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
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