Title:
Purine derivatives for the treatment of viral infections
Document Type and Number:
Japanese Patent JP6349256
Kind Code:
B2
Abstract:
The present invention relates to purine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.
Inventors:
Bonfanati, Jean-Francois
Doubre, Frederick Mark Maurice
Emblets, berner
Fortin, Jerome Michel Claude
MC Gowan, David Craig
Mueller filippe
La Boisson, Pierre Jean-Marie Bernardo
Doubre, Frederick Mark Maurice
Emblets, berner
Fortin, Jerome Michel Claude
MC Gowan, David Craig
Mueller filippe
La Boisson, Pierre Jean-Marie Bernardo
Application Number:
JP2014540449A
Publication Date:
June 27, 2018
Filing Date:
November 08, 2012
Export Citation:
Assignee:
Janssen Sciences Ireland Ireland
International Classes:
C07D473/34; A61K31/522; A61K31/675; A61P29/00; A61P31/12; A61P37/02; A61P43/00; C07D519/00; C07F9/6561
Domestic Patent References:
| JP2010532353A | ||||
| JP2010522151A | ||||
| JP2009528989A |
Foreign References:
| WO2011049825A1 | ||||
| WO2008114819A1 | ||||
| WO2007034881A1 | ||||
| WO2005092892A1 | ||||
| WO1999032122A1 | ||||
| WO1998001448A1 | ||||
| US20140148433 |
Other References:
MUSMUCA, Ira et al.,Small-Molecule Interferon Inducers. Toward the Comprehension of the Molecular Determinants through Ligand-Based Approaches,J. Chem. Inf. Model.,2009年,Vol.49,pp.1777-1786
ISOBE, Yoshiaki et al.,Synthesis and Structure-Activity Relationships of 2-Substituted-8-hydroxyadenine Derivatives as Orally Available Interferon Inducers without Emetic Side Effects,Bioorganic & Medicinal Chemistry,2003年,Vol.11,pp.3641-3647
TRAN, Thien-Duc et al.,Design and optimisation of orally active TLR7 agonists for the treatment of hepatitis C virus infection,Bioorganic & Medicinal Chemistry Letters,2011年,Vol.21,pp.2389-2393
ISOBE, Yoshiaki et al.,Synthesis and Structure-Activity Relationships of 2-Substituted-8-hydroxyadenine Derivatives as Orally Available Interferon Inducers without Emetic Side Effects,Bioorganic & Medicinal Chemistry,2003年,Vol.11,pp.3641-3647
TRAN, Thien-Duc et al.,Design and optimisation of orally active TLR7 agonists for the treatment of hepatitis C virus infection,Bioorganic & Medicinal Chemistry Letters,2011年,Vol.21,pp.2389-2393
Attorney, Agent or Firm:
Hiroshi Kobayashi
Junko Kobayashi
Norio Omori
Saori Oga
Yasuhito Suzuki
Junko Kobayashi
Norio Omori
Saori Oga
Yasuhito Suzuki
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