A pyrazolo [3 and 4-d] pyrimidine compound, its manufacture, and use as a sigma ligand

Title:

A pyrazolo [3 and 4-d] pyrimidine compound, its manufacture, and use as a sigma ligand

Document Type and Number:

Japanese Patent JP6074775

Kind Code:

B2

Abstract:

The present invention relates to new pyrazolo[3,4- d ]pyrimidine compounds having a great affinity for sigma receptors, especially sigma-1 receptors as well as to the process for the preparation thereof, to composition comprising them and to their use as medicaments.

Inventors:

Cuberes-Altissen, Maria, Rosa
Corvera-Arhona, Jordi
Diaz-Fernandez, Jose, Lewis
Almansa-Rosales, Carmen

Application Number:

JP2014520620A

Publication Date:

February 08, 2017

Filing Date:

July 13, 2012

Export Citation:

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Assignee:

Laboratorios del Deere Esteve Ese A

International Classes:

C07D487/04; A61K31/519; A61K31/5377; A61K31/55; A61K31/551; A61K31/553; A61P1/04; A61P3/04; A61P3/06; A61P7/00; A61P9/06; A61P9/10; A61P9/12; A61P19/02; A61P25/04; A61P25/06; A61P25/08; A61P25/18; A61P25/22; A61P25/24; A61P25/28; A61P25/30; A61P25/32; A61P25/36; A61P27/06; A61P29/00; A61P31/04; A61P35/00; A61P37/06; A61P43/00

Domestic Patent References:

JP2011504927A
JP2009517419A
JP2011504913A
JP2008510768A
JP2010509281A
JP2005531584A
JP2011503103A
JP2007534687A

Foreign References:

WO2010084300A1
WO2001010880A1
WO2010003475A1

Other References:

ROSEMEYER HELMUT,SYMMETRICALLY AND UNSYMMETRICALLY BRIDGED METHYLENEBIS(ALLOPURINOLS): 以下備考,MOLECULES [ONLINE],Vol.12 No.3,P.563-575,SYNTHESIS OF DIMERIC POTENTIAL ANTI-GOUT DRUGS,URL,HTTP://WWW.MDPI.ORG/MOLECULES/PAPERS/12030563.PDF
Antibiotics and Chemotherapy,1959年,Vol.9,p.333-336
LEONOVA T. S.,SOME REACTIONS OF 4-AMINOPYRAZOLO[3,4-D]PYRIMIDINES,CHEMISTRY OF HETEROCYCLIC COMPOUNDS,1982年,Vol.18 No.7,P.753-755

Attorney, Agent or Firm:

Yuriko Hamada
Furudate Kutanko
Tomoko Yamazaki

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