Title:
The pyrimidine derivative as FAK inhibitor
Document Type and Number:
Japanese Patent JP6049617
Kind Code:
B2
Abstract:
Compounds of the formula (I), in which R1, R2 and R3 have the meanings indicated in Claim 1, are kinase inhibitors and can be employed, inter alia, for the treatment of tumors.
Inventors:
Heinrich, Timo
Esdahl, Christina
Greiner, Hartmut
Esdahl, Christina
Greiner, Hartmut
Application Number:
JP2013524362A
Publication Date:
December 21, 2016
Filing Date:
July 19, 2011
Export Citation:
Assignee:
Merck Patent Gesellschaft mit beschraenkter Haftung
International Classes:
A61K31/505; C07D239/42; A61K31/506; A61K31/5377; A61P1/16; A61P3/00; A61P3/10; A61P7/02; A61P9/00; A61P9/10; A61P13/12; A61P17/00; A61P17/02; A61P17/06; A61P19/02; A61P19/08; A61P25/00; A61P27/02; A61P29/00; A61P35/00; A61P35/02; A61P35/04; A61P37/02; A61P37/06; A61P37/08; A61P43/00; C07D239/48; C07D401/06; C07D401/12; C07D401/14; C07D403/04; C07D403/12; C07D405/04; C07D413/12; C07D413/14; C07D417/04; C07D417/12
Domestic Patent References:
| JP2005509624A | ||||
| JP2006515298A |
Foreign References:
| WO2010058030A1 |
Other References:
BLANK B. et al,Catalytic Alkylation of Methyl-N-Heteroaromatics with Alcohols,JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,2010年,Vol. 132, No. 3,p. 924-925
MATSUKAWA T. et al,Reactions of 2-aminopyrimidines with aromatic aldehydes. I,YAKUGAKU ZASSHI,1952年,Vol. 72, No. 7,p. 909-912
MATSUKAWA T. et al,Reactions of 2-aminopyrimidines with aromatic aldehydes. I,YAKUGAKU ZASSHI,1952年,Vol. 72, No. 7,p. 909-912
Attorney, Agent or Firm:
Kiyoji Kuzuwa