Title:
A quinoline compound replaced alternatively
Document Type and Number:
Japanese Patent JP6223563
Kind Code:
B2
Abstract:
Embodiments of the disclosure relate to selectively substituted quinoline compounds that act as antagonists or inhibitors for Toll-like receptors 7 and/or 8, and their use in pharmaceutical compositions effective for treatment of systemic lupus erythematosus (SLE) and lupus nephritis.
Inventors:
Carlson, Eric
Hansen, Hans
Mackey, matthew
Schiller, Shawn
Ogawa, Chikako
Davis, Heather
Pea, Atsushi
Hawkins, Lynn
Sari, sari
Hansen, Hans
Mackey, matthew
Schiller, Shawn
Ogawa, Chikako
Davis, Heather
Pea, Atsushi
Hawkins, Lynn
Sari, sari
Application Number:
JP2016523329A
Publication Date:
November 01, 2017
Filing Date:
October 14, 2014
Export Citation:
Assignee:
Eisai R & D Management Co., Ltd.
International Classes:
A61K31/47; C07D413/04; A61K31/4709; A61K31/497; A61K31/5377; A61K31/55; A61K31/551; A61K31/553; A61P13/12; A61P37/02; A61P43/00; C07D215/48; C07D401/10; C07D413/14; C07D417/14; C07D451/04; C07D471/04; C07D471/10; C07D487/04; C07D487/10; C07D491/107
Domestic Patent References:
| JP2013028588A | ||||
| JP2007524615A | ||||
| JP2005132834A | ||||
| JP2000510865A |
Foreign References:
| CN1528748A |
Other References:
Joint Bone Spine,2010年,Vol.77, No.1,pp.4-5,ISSN:1297-319X, DOI:10.1016/j.jbspin.2009.09.007
Attorney, Agent or Firm:
Yoshiyuki Inaba
Toshifumi Onuki
Akihiko Eguchi
Kazuhiko Naito
Toshifumi Onuki
Akihiko Eguchi
Kazuhiko Naito