Title:
感染症および炎症のイメージング用放射性医薬品
Document Type and Number:
Japanese Patent JP2001525796
Kind Code:
A
Abstract:
The present invention provides novel radiopharmaceutials useful for the diagnosis of infection and inflammation, reagents and kits useful for preparing the radiopharmaceuticals, methods of imaging sites of infection and/or inflammation in a patient, and methods of diagnosing diseases associated with infection or inflammation in patients in need of such diagnosis. The radiopharmaceuticals bind in vivo to the leukotriene B4 (LTB4) receptor on the surface of leukocytes which accumulate at the site of infection and inflammation. The reagents provided by this invention are also useful for the treatment of diseases associated with infection and inflammation.
Inventors:
チースマン，エドワード，ホリスター．
ハリス，トーマス，デイヴィッド．
バレット，ジョン，アンドリュー．
ラジヨパディー，ミリンド．
ハリス，トーマス，デイヴィッド．
バレット，ジョン，アンドリュー．
ラジヨパディー，ミリンド．
Application Number:
JP51768098A
Publication Date:
December 11, 2001
Filing Date:
October 06, 1997
Export Citation:
Assignee:
デュポン ファーマシューティカルズ カンパニー
International Classes:
A61K31/44; A61K31/443; A61K31/4433; A61K31/4439; A61K31/4545; A61K51/00; A61K51/04; A61P29/00; A61P31/04; C07C69/734; C07C323/41; C07D213/64; C07D213/71; C07D213/77; C07D213/82; C07D401/06; C07D401/12; C07D401/14; C07D405/04; C07D405/12; C07D405/14; C07H15/12; (IPC1-7): C07D213/82; A61K31/44; A61K31/443; A61K31/4433; A61K31/4439; A61K31/4545; A61K51/00; A61P29/00; A61P31/04; C07D213/64; C07D213/71; C07D401/06; C07D401/12; C07D401/14; C07D405/12; C07D405/14
Attorney, Agent or Firm:
谷 義一 （外２名）