Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
安定な放射性ヨウ素複合体の精製方法
Document Type and Number:
Japanese Patent JP2006517230
Kind Code:
A
Abstract:
The present invention is directed toward a method for preparing and purifying a conjugate of a radioiodinated aminopolycarboxylate-appended peptide and a targeting agent. The method involves (A) providing a solution comp rising (i) unbound radioiodine (ii) a radioiodinated aminopolycarboxylate-appended peptide that is not conjugated to a targeting agent (iii) and a radioiodinated aminopolycarboxylate-appended peptide that is conjugated to the targeting agent; (B) contacting the solution with an anion-exchange resin; and (C) passing the anion-exchange resin and solution together through a filter capable of trapping anion-exchange resin particles.

Inventors:
Serengram, buoy. Gobindan
Application Number:
JP2006503348A
Publication Date:
July 20, 2006
Filing Date:
February 04, 2004
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
IMMUNOMEDICS, INC.
International Classes:
A61K51/00; A61K38/00; A61K51/04; A61K51/08; A61K51/10; A61M36/00; A61N1/00; A61P1/04; A61P1/16; A61P3/10; A61P7/06; A61P9/00; A61P13/12; A61P19/08; A61P21/00; A61P21/04; A61P25/00; A61P25/14; A61P25/28; A61P29/00; A61P31/00; A61P35/00; A61P37/06; C07H3/04; C07K1/107; G01N33/543; A61N
Foreign References:
WO1998008548A21998-03-05
Attorney, Agent or Firm:
Kenji Yoshitake
Yukitaka Nakamura
Konno Akio
Noritaka Yokota