EXPERIMENTAL APPARATUS FOR REPRODUCING PATHOLOGICAL CONDITION OF GLAUCOMA AND SCREENING METHOD USING SAME

Japanese Patent JP2018050537

A

PROBLEM TO BE SOLVED: To provide a glaucoma model that can accurately reproduce the pathological condition of glaucoma.SOLUTION: An experimental apparatus (1) is provided that comprises: A) a pressurized container (2); B) a culture vessel (3) housing retinal tissue (5) and a culture solution (4) therein; C) a gas blender (6) for blending two pressurized gases provided with an inert gas flow control valve (9) and an oxygen gas flow control valve (10); D) a gas injection pipe (12); E) a pressure control valve (14); F) a dissolved oxygen concentration sensor (16); G) a dissolved oxygen concentration input unit (18) which receives the measured value of the dissolved oxygen concentration sensor and which sets the dissolved oxygen concentration to any value. The experimental apparatus (1) further comprises a control device (11) controlling the inert gas flow control valve and/or the oxygen gas flow control valve such that the measured value of the dissolved oxygen concentration sensor matches the value set by the dissolved oxygen concentration input unit.SELECTED DRAWING: Figure 1

ISHIKAWA MAKOTO
YOSHITOMI TAKESHI
KAMI DAISUKE
TAKAZAKI SANAE

JP2016190732A

April 05, 2018

September 29, 2016

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UNIV AKITA

C12M3/00; A61K31/56; A61K45/00; A61P27/06; C12M1/34; C12Q1/04; G01N33/15; G01N33/50

JP2004242581A	2004-09-02
JPH06153910A	1994-06-03

Takaaki Nagashima
Takuya Yano
Shunsuke Wakayama

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