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Title:
長さが変動性であるクロマトグラフィー帯域を用いる分離方法
Document Type and Number:
Japanese Patent JP4966449
Kind Code:
B2
Abstract:
A process for separating at least one component of a mixture in a set of closed-loop chromatographic columns is described, whereby the loop comprises at least one feedstock injection point, a raffinate draw-off point, an eluant injection point, and an extract draw-off point, in which a determination is made between an injection point and a draw-off point or vice-versa a chromatographic zone, and at the end of a given period of time, all of the injection and draw-off points are shifted by one column or column section in a given direction that is defined relative to that of the flow of a main fluid that circulates through the loop. During the period, the shifting of different injection and draw-off points of a column or column section is done at different times in such a way that the lengths of the zones that are defined by said different points are variable. The process is useful for the seperation particularly of stereoisumers for pharmaceuticals.

Inventors:
By michel
Adhan Philip
Lyudman Ohmburger Olivier
Niku Roger Marc
Application Number:
JP2000579318A
Publication Date:
July 04, 2012
Filing Date:
October 29, 1999
Export Citation:
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Assignee:
INSTITUT FRANCAIS DU PETROL
Nova Sep
International Classes:
G01N30/46; B01D15/08; B01D15/18; C07B57/00; C07B63/00; C07C33/025; C07C33/34; G01N30/02; G01N30/88
Domestic Patent References:
JPH08178908A1996-07-12
JPH0843372A1996-02-16
JPS614503A1986-01-10
JP54011150B
JPH04334503A1992-11-20
JPH06170111A1994-06-21
JPH0695090B21994-11-24
Foreign References:
FR2754730A11998-04-24
Attorney, Agent or Firm:
Einosuke Kishimoto
Moriichi Kishimoto
Akira Watanabe
Norihiko Hibi