Title:
固形製剤
Document Type and Number:
Japanese Patent JP7355097
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To provide controlled release formulations containing ibuprofen and other amino group-containing compound, the formulations being controlled so that elution of the amino group-containing compound is not dependent on pH.SOLUTION: In order to achieve the above-mentioned subject, we found that when compounding organic acid or acidic amino acid with a controlled release formulation which contains ibuprofen and an amino group-containing compound, the controlled releasability of amino acid-containing compound is not affected by pH, and completed the invention. That is, the invention is a solid preparation characterized by (1) containing (a) ibuprofen, (b) an amino group-containing compound or salts thereof, (c) a release control base, and (d) an organic acid or an acidic amino acid.SELECTED DRAWING: Figure 3
Inventors:
Kazuhiro Ishii
East treetop
Masamichi Nishijima
East treetop
Masamichi Nishijima
Application Number:
JP2021175268A
Publication Date:
October 03, 2023
Filing Date:
October 27, 2021
Export Citation:
Assignee:
Taisho Pharmaceutical Co., Ltd.
International Classes:
A61K31/192; A61K9/22; A61K31/485; A61K47/10; A61K47/12; A61K47/22; A61K47/32; A61K47/36; A61K47/38; A61P11/10; A61P29/00; A61P43/00
Domestic Patent References:
| JP2015107951A | ||||
| JP2006096749A | ||||
| JP2009235020A | ||||
| JP2004217566A |
Other References:
薬理と治療,1998年,Vol.26, No.6,pp.1019-1026