ALKYL CELLULOSE FOR TABLETING, AND SOLID PREPARATION CONTAINING THE SAME

Japanese Patent JP2016084469

A

PROBLEM TO BE SOLVED: To provide alkyl cellulose excellent in moldability with a low addition amount and not significantly retarding collapsibility, a solid preparation containing the same, and a method for producing the solid preparation.SOLUTION: The alkyl cellulose has a specific surface area measured by a BET method of 0.5-10.0 m/g. The solid preparation contains at least the alkyl cellulose. The method for producing alkyl cellulose for tableting at least includes: a process of contacting pulp with an alkali metal hydroxide solution to obtain alkali cellulose; a process of reacting the alkali cellulose with etherification reagent to obtain a first alkyl cellulose; pulverizing the first alkyl cellulose; and a process of depolymerizing the pulverized first alkyl cellulose by hydrolysis using an acid catalyst or oxidative decomposition using an oxidizer to obtain a second alkyl cellulose.SELECTED DRAWING: None

JPS5811882	[Title of the Invention] A manufacturing method of water-soluble cellulose ether which carries out the distributed dissolution easily not related to PH field of a water solvent
WO/2001/077183	METHOD FOR THE PRODUCTION OF EASILY WETTED, WATER-SOLUBLE, POWDERED AT LEAST ALKYLATED NON-IONIC CELLULOSE ETHERS
JPS55145701	METHOD OF LOWERING CELLULOSE ETHER VISCOSITY WITH OZONE

YOKOZAWA TAKUYA
MARUYAMA NAOAKI

JP2015207352A

May 19, 2016

October 21, 2015

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SHINETSU CHEMICAL CO

C08B11/02; A61K9/20; A61K47/38; C08B11/20

JP2015166453A	2015-09-24
JP2008133258A	2008-06-12
JP2012211340A	2012-11-01
JP2014148668A	2014-08-21

WO1992003167A1

1992-03-05

Shoichi Okuyama
Arihara Koichi
Matsushima Tetsuo
Hidefumi Kawamura
Ayako Nakamura
Satoshi Morimoto
Yu Tanaka
Tokumoto Koichi

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