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Title:
A spraying device in a nose
Document Type and Number:
Japanese Patent JP6050236
Kind Code:
B2
Abstract:
This invention relates to a nasal spray device (1) for the delivery of a pharmaceutical formulation to the nasal cavity in metered doses. The device comprises: a pressurised aerosol canister (3) including a vial (4) containing a pharmaceutical formulation comprising an active ingredient, a propellant and, optionally, a co- solvent, the aerosol canister further including a metering valve (6) having a valve stem (8); and an actuator (2) for the aerosol canister, the actuator including a stem block (11) having a receptacle into which the valve stem of metering valve of the aerosol canister is received and axially located and being displaceable relative to the vial of the aerosol canister to actuate the metering valve of the aerosol canister, a sump (15) extending below the receptacle, the stem block further defining a discharge orifice (19) for the pharmaceutical formulation and a transfer channel (13) through which a dispensed dose of the pharmaceutical formulation is able to pass from the sump to the discharge orifice. The actuator further comprises a delivery outlet (12) for the aerosol plume, the discharge orifice being arranged to direct the aerosol plume through the delivery outlet, and wherein the device is adapted to produce an aerosol plume for a dispensed dose having a spray force value no greater than 40 mN measured at a distance of 30 mm from the discharge orifice. Use of the term formulation encompasses both solution and suspension formulations.

Inventors:
Declan Walsh
Zeng, Shan-ming
Lee, Jade
Morales, Armand
Application Number:
JP2013533127A
Publication Date:
December 21, 2016
Filing Date:
October 12, 2011
Export Citation:
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Assignee:
Ivacs Pharmaceuticals Ireland
Teva Branded Pharmaceutical Products R&D Incorporated
International Classes:
A61M11/06
Domestic Patent References:
JP2001299915A
JP2010531688A
JP2003522081A
JP2010519963A
Attorney, Agent or Firm:
Patent Business Corporation Minori Patent Office