Title:
癌の治療のための物質または組成物
Document Type and Number:
Japanese Patent JP2004524284
Kind Code:
A
Abstract:
A substance for use in the treatment of cancer, includes a compound selected from metallocenyl beta-diketones Mc-CO-CZ1Z2-CO-R. Mc is Fc (ferrocenyl), Rc (ruthenocenyl) or Oc (osmocenyl), R is 11, alkyl or aryl and Z1 and Z2 are H, alkyl, aryl or substituted alkyl, ferrocenyl, the enol forms of the beta-diketones and metal complexes of the beta-diketones of the general formula M(beta-diketonato)A<1>, M(beta-diketonato)A<1>A<2>, M(beta-diketonato)A<1>B<1>B<2>, M(beta-diketonato)B<1>B<2 >and M(beta-diketonato)B<1>B<2>B<3>B<4>. M is Rh or Ir, A<1 >and A<2 >are cyclic dienes having 6-8 carbons, or linear alkenes having 2-7 carbons. B<1>, B<2>, B<3 >and B<4 >are selected from CO, P(R<1>R<2>R<3>), P(OR<1>)(OR<2>)(OR<3>), R<4 >and X in which R<1>, R<2>, R<3 >and R<4 >are independently alkyl, phenyl or ferrocenyl, and X is a halide or a pseudohalide.
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Inventors:
Swarts, Johannes, Christian
Medlen, Constance, Elizabeth
Medlen, Constance, Elizabeth
Application Number:
JP2002547940A
Publication Date:
August 12, 2004
Filing Date:
November 29, 2001
Export Citation:
Assignee:
UNIVERSITY OF PRETORIA
UNIVERSITY OF THE FREE STATE
UNIVERSITY OF THE FREE STATE
International Classes:
A61K31/28; A61K31/295; A61P35/04; C07F15/00; C07F15/02; C07F17/02; A61P35/00; C07F19/00; (IPC1-7): A61K31/28; A61K31/295; A61P35/00; C07F15/00; C07F15/02; C07F19/00
Attorney, Agent or Firm:
Yasuo Ishikawa