Title:
【発明の名称】置換ジベンズ[a,f]アズレンおよび調製方法
Document Type and Number:
Japanese Patent JPH11502521
Kind Code:
A
Abstract:
Tetracyclic compounds having the following structure are described: wherein R1-R10 are as defined. The tetracyclic compounds are capable of potent effects on steroid sensitive tissues and have demonstrated increased uterine weight, antiovulatory effects and potent steroid receptor binding. The compounds have therapeutic utility in reproductive applications such as fertility control, labor induction, ovulation induction and spermatogenesis. Methods for preparing the tetracyclic compounds from substituted indanones are also described.
Inventors:
Joo Yeon Yee
Dixon, Lisa A
Barrington, The Ames El
Shwender, Chyar F
Dixon, Lisa A
Barrington, The Ames El
Shwender, Chyar F
Application Number:
JP52762996A
Publication Date:
March 02, 1999
Filing Date:
March 07, 1996
Export Citation:
Assignee:
ORTHO PHARMACEUTICAL CORPORATION
International Classes:
A61K31/03; A61K31/04; A61K31/085; A61K31/12; A61K31/135; A61K31/165; A61K31/215; A61P13/02; A61P15/00; C07C13/66; C07C23/46; C07C25/22; C07C39/17; C07C43/21; C07C43/215; C07C43/225; C07C43/23; C07C49/755; C07C49/84; C07C65/26; C07C69/00; C07C69/157; C07C69/65; C07C69/734; A61K31/015; C07C205/20; C07C205/37; C07C205/42; C07C211/61; C07C217/16; C07C217/24; C07C233/07; C07C233/11; C07C233/15; C07D257/04; C07F9/12; (IPC1-7): C07C13/66; A61K31/015; A61K31/03; A61K31/04; A61K31/085; A61K31/12; A61K31/135; A61K31/165; A61K31/215; C07C23/46; C07C25/22; C07C39/17; C07C43/21; C07C43/215; C07C43/225; C07C43/23; C07C49/755; C07C65/26; C07C69/157; C07C69/65; C07C69/734; C07C211/61; C07C217/16; C07C233/11
Attorney, Agent or Firm:
Heiyoshi Odashima