Title:
トランス-4-((1R,3S)-6-クロロ-3-フェニルインダン-1-イル)-1,2,2-トリメチルピペラジンのコハク酸塩およびマロン酸塩、および薬剤としての使用方法
Document Type and Number:
Japanese Patent JP2007502783
Kind Code:
A
Abstract:
Methods for the preparation of 4-((1R,3S)-6-Chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine and salts thereof are described.
Inventors:
Lopez de Diego Haydy
Nielsen Ole
Linkaah Rone Munch
Svane Henrik
Dar Allan Karsten
Hovells Merck
Bank-Andersen Benny
Links Lars Ole
Nielsen Ole
Linkaah Rone Munch
Svane Henrik
Dar Allan Karsten
Hovells Merck
Bank-Andersen Benny
Links Lars Ole
Application Number:
JP2006523528A
Publication Date:
February 15, 2007
Filing Date:
August 18, 2004
Export Citation:
Assignee:
Her Lundbeck Actiezer Scabet
International Classes:
C07D241/04; A61K31/495; A61P25/00; A61P25/06; A61P25/18; A61P25/20; A61P25/22; A61P25/24; A61P25/30; A61P25/32; A61P25/34; C07C17/16; C07C23/24; C07C25/22; C07C25/24; C07C29/143; C07C35/32; C07D295/073; C12P7/22; C12P41/00
Domestic Patent References:
| JPH07505895A | 1995-06-29 | |||
| JP2002531568A | 2002-09-24 | |||
| JPH06184132A | 1994-07-05 | |||
| JP2003502309A | 2003-01-21 | |||
| JP2003509337A | 2003-03-11 | |||
| JP2000351773A | 2000-12-19 | |||
| JP2003502294A | 2003-01-21 | |||
| JP2002517386A | 2002-06-18 | |||
| JP2002516314A | 2002-06-04 | |||
| JP2001503446A | 2001-03-13 |
Other References:
BOGESO KP ET AL, JOURNAL OF MEDICINAL CHEMISTRY, vol. 38, JPN6010072305, 1995, pages 4380 - 4392, ISSN: 0001808762
BASTIN,R.J. ET AL: "Salt selection and optimization procedures for pharmaceutical new chemical entities", ORGANIC PROCESS RESEARCH & DEVELOPMENT, vol. 4, no. 5, JPN6009059058, 2000, pages 427 - 435, ISSN: 0001808763
BASTIN,R.J. ET AL: "Salt selection and optimization procedures for pharmaceutical new chemical entities", ORGANIC PROCESS RESEARCH & DEVELOPMENT, vol. 4, no. 5, JPN6009059058, 2000, pages 427 - 435, ISSN: 0001808763
Attorney, Agent or Firm:
Mitsufumi Esaki
Okumura Yoshimichi
Blacksmith
Okumura Yoshimichi
Blacksmith