Title:
プロパルギル化アミノインダン誘導体の合成方法
Document Type and Number:
Japanese Patent JP5425806
Kind Code:
B2
Abstract:
A process for preparing a compound of formula (V) or its enantiomer, which comprises: (a) reacting racemic aminoindan of formula (II) or its enantiomer with allylhalide in presence of a base and an organic solvent at a temperature ranging from 25 C to the reflux temperature of the solvent to give compound of formula (III); Where R is H or (b) reacting the compound (III) with halogenating agent in a suitable organic solvent to give a dihalo compound of formula (IV). (c) treating the dihalo compound (IV) with a suitable base to give compound (V).
Inventors:
Mangin del Singh Phufululu
Dohar Marajer Ramachandra Rao
Rajendra Narayan Rao Cancan
Dohar Marajer Ramachandra Rao
Rajendra Narayan Rao Cancan
Application Number:
JP2010540170A
Publication Date:
February 26, 2014
Filing Date:
December 19, 2008
Export Citation:
Assignee:
Shipra Limited
International Classes:
C07C209/74; C07B57/00; C07C209/88; C07C211/42
Domestic Patent References:
| JP3294248A | ||||
| JP9505806A | ||||
| JP2009521402A | ||||
| JP2008531546A | ||||
| JP11080139A | ||||
| JP2003523991A |
Foreign References:
| US3123642 | ||||
| US3513244 |
Attorney, Agent or Firm:
Toru Ishikawa