Title:
The system for delivery into a XCR1 positivity cell, and its use
Document Type and Number:
Japanese Patent JP5946494
Kind Code:
B2
Abstract:
The present invention relates to a delivery system suitable for delivering a substance into a XCR1 positive professional antigen-presenting cell, one or more nucleic acids coding for the same, a vector comprising the nucleic acid(s), a medicament comprising the delivery system or the one or more nucleic acid(s) and an adjuvant comprising XCL1 or a functionally active fragment thereof.
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Inventors:
Crocek Richard
Application Number:
JP2014150090A
Publication Date:
July 06, 2016
Filing Date:
July 23, 2014
Export Citation:
Assignee:
Bundes Republik Germany Land Let's Bartleten Darch das Robert Kosh-Institut Bartleten Darch Seinen Pradenten
International Classes:
A61K47/48; A61K39/00; A61K39/39; A61K47/42; A61P31/00; A61P35/00; A61P37/06; A61P37/08
Domestic Patent References:
| JP2001526240A |
Other References:
石井 保之,免疫制御リボソームによる根本的治療,別冊・医学のあゆみ 上気道アレルギー疾患研究,2007年 3月,第59-63頁
HSPを用いた免疫増強とHLA消失による免疫回避,医学のあゆみ,2007年 5月,第221巻,第8号,第627-630頁
赤木 隆美,高分子ナノ微粒子を用いるワクチンの開発,日本臨牀,2006年,第64巻,第2号,第279-285頁
東 市郎,合成免疫アジュバントの開発とMDP-抗原結合ワクチン,日本臨牀,遠藤 武男,1987年,第45巻,第10号,第155-161頁
Lymphotactin gene-modified bone marrow dendritic cells act as more potent adjuvants for peptide delivery to induce specific antitumor immunity. ,Journal of immunology,Vol.161,No.11,1998年,pp.6238-44.
HSPを用いた免疫増強とHLA消失による免疫回避,医学のあゆみ,2007年 5月,第221巻,第8号,第627-630頁
赤木 隆美,高分子ナノ微粒子を用いるワクチンの開発,日本臨牀,2006年,第64巻,第2号,第279-285頁
東 市郎,合成免疫アジュバントの開発とMDP-抗原結合ワクチン,日本臨牀,遠藤 武男,1987年,第45巻,第10号,第155-161頁
Lymphotactin gene-modified bone marrow dendritic cells act as more potent adjuvants for peptide delivery to induce specific antitumor immunity. ,Journal of immunology,Vol.161,No.11,1998年,pp.6238-44.
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto