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Title:
The tablet of SKY inhibitor
Document Type and Number:
Japanese Patent JP6153667
Kind Code:
B2
Abstract:
or a pharmaceutically acceptable salt thereof, or a hydrate of thereof, and at least one pharmaceutically acceptable polymer. The pharmaceutically acceptable salt of the compound of Formula I, or a hydrate thereof, can be a mesylate salt, including, for example, a mono-mesylate or a bis-mesylate salt, or a hydrate thereof. Also disclosed are methods of use for the pharmaceutical composition.

Inventors:
Li, bay
Superger, Diana
Stefanidis, Dimitrios
Castile, Melissa Jean
Pakdaman, Rochanaku
Application Number:
JP2016531839A
Publication Date:
June 28, 2017
Filing Date:
July 29, 2014
Export Citation:
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Assignee:
Gilead Connecticut, Incorporated
International Classes:
A61K31/5377; A61K9/14; A61K9/20; A61K47/04; A61K47/10; A61K47/12; A61K47/24; A61K47/38; A61K47/58; A61P11/06; A61P19/02; A61P25/00; A61P29/00; A61P35/00; A61P35/02; A61P37/02; A61P37/06; A61P43/00
Domestic Patent References:
JP2012510997A
JP2013514349A
JP2016527268A
Other References:
小嶌隆史,医薬品開発における結晶性選択の効率化を目指して,薬剤学,2008年 9月 1日,Vol.68, No.5,p.344-349
芦澤一英,塩・結晶形の最適化と結晶化技術,Pharm Tech Japan,2002年,Vol.18, No.10,pp.81-96
高田則幸,創薬段階における原薬Formスクリーニングと選択,PHARM STAGE,2007年 1月15日,Vol.6, No.10,p.20-25
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto