Title:
The use as a pyrazol derivative and inhibitor of DLK
Document Type and Number:
Japanese Patent JP6228310
Kind Code:
B2
Abstract:
The present invention provides for compounds of formula 0 and various embodiments thereof, and compositions comprising compounds of formula 0 and various embodiments thereof. In compounds of formula 0, the groups R1A, R1B, R1C, R1D, R2, R3, R4, R5 and R6 have the meaning as described herein. The present invention also provides for methods of using compounds of formula 0 and compositions comprising compounds of formula 0 as DLK inhibitors and for treating neurodegeneration diseases and disorders.
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Inventors:
Lysikatos, Joseph Pee
Riu, Wen
Shu, Michael
Estrada, Anthony
Patel, Snahel
Liang, Gui Bai
Houstis, Malcolm
Chen, Kevin
Riu, Wen
Shu, Michael
Estrada, Anthony
Patel, Snahel
Liang, Gui Bai
Houstis, Malcolm
Chen, Kevin
Application Number:
JP2016541483A
Publication Date:
November 08, 2017
Filing Date:
December 19, 2014
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
C07D401/04; A61K31/4439; A61K31/496; A61K31/4985; A61K31/499; A61K31/4995; A61K31/5377; A61K31/538; A61K31/5383; A61K31/5386; A61K31/541; A61K31/551; A61K31/553; A61K45/00; A61P7/04; A61P9/10; A61P19/04; A61P21/02; A61P21/04; A61P25/00; A61P25/02; A61P25/04; A61P25/08; A61P25/14; A61P25/16; A61P25/20; A61P25/28; A61P27/02; A61P27/06; A61P39/02; A61P43/00; C07D401/14; C07D405/14; C07D413/14; C07D471/04; C07D487/04; C07D487/08; C07D491/048; C07D491/08; C07D491/107; C07D498/04; C07D498/10
Domestic Patent References:
| JP2011530485A |
Foreign References:
| WO2013180271A1 | ||||
| WO2013174780A1 | ||||
| WO2011050192A1 |
Attorney, Agent or Firm:
Patent business corporation Tsukuni