Title:
合成大環状アミドHDAC6阻害剤化合物およびそれらの治療剤としての用途
Document Type and Number:
Japanese Patent JP2013508323
Kind Code:
A
Abstract:
The present invention relates to novel amide compounds of formula I, and their use as anti-tumoral and pro-apoptotic agents. The invention includes the use of such compounds in medicine, in relation to cancer disease as well as other diseases where an inhibition of HDAC6 is responsive, and the pharmaceutical composition containing such compounds.
Inventors:
Giuseppe Giannini
Walter Kaburi
Stephan Heinshan
Luciana Autzas
Andreas Larson
Walter Kaburi
Stephan Heinshan
Luciana Autzas
Andreas Larson
Application Number:
JP2012534605A
Publication Date:
March 07, 2013
Filing Date:
September 21, 2010
Export Citation:
Assignee:
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE SOCIETA PER AZIONI
International Classes:
C07D273/02; A61K31/395; A61K31/407; A61P19/02; A61P25/00; A61P29/00; A61P33/06; A61P35/00; A61P43/00; C07D498/04
Foreign References:
| WO2008110583A1 | 2008-09-18 | |||
| WO2009022182A1 | 2009-02-19 | |||
| WO2007061939A2 | 2007-05-31 |
Attorney, Agent or Firm:
Aoyama Aoi
Takuji Yamada
Michiko Matsutani
Sakurai Yoko
Satoshi Hashimoto
Takuji Yamada
Michiko Matsutani
Sakurai Yoko
Satoshi Hashimoto