Title:
気道に影響する増殖性疾患の処置に有用な製剤
Document Type and Number:
Japanese Patent JP6595463
Kind Code:
B2
Abstract:
The present application provides a pharmaceutical formulation comprising a folate receptor (FR)-targeting antineoplastic substance or composition, wherein the pharmaceutical formulation is configured for administration by inhalation, wherein the FR-targeting antineoplastic substance or composition is comprised in a nanoparticle and wherein the nanoparticles are comprised in microparticles, and its use in the treatment of a proliferative disease affecting at least part of the respiratory tract. The present application further provides a pharmaceutical formulation comprising an antineoplastic agent and a FR-targeting excipient, for use in the treatment of a proliferative disease affecting at least part of the respiratory tract.
Inventors:
Amigi, Karim
Rosier, Remi
Wouts, Natalie
Gerbuk, Michel
Rosier, Remi
Wouts, Natalie
Gerbuk, Michel
Application Number:
JP2016524506A
Publication Date:
October 23, 2019
Filing Date:
October 16, 2014
Export Citation:
Assignee:
Université Libre de Brussels
International Classes:
A61K47/36; A61K9/14; A61K31/337; A61K31/4188; A61K31/4745; A61K31/475; A61K31/675; A61K31/704; A61K31/7048; A61K31/7068; A61K33/243; A61K45/00; A61P35/00
Domestic Patent References:
| JP2005008598A |
Foreign References:
| WO2012174559A1 | ||||
| US20120269729 |
Other References:
Int J Pharm Pharm Sci,2012年,Vol.4, Issue 3,p.163-169
Attorney, Agent or Firm:
Yoshiyuki Kawaguchi
Shinichi Sanuki
Takeshi Niwa
Toshiaki Shimoda
Shinichi Sanuki
Takeshi Niwa
Toshiaki Shimoda