Title:
A vaccine constituent containing a synthetic adjuvant
Document Type and Number:
Japanese Patent JP6190031
Kind Code:
B2
Abstract:
Compositions and methods, including vaccines and pharmaceutical compositions for inducing or enhancing an immune response are disclosed based on the discovery of useful immunological adjuvant properties in a synthetic, glucopyranosyl lipid adjuvant (GLA) that is provided in substantially homogenous form. Chemically defined, synthetic GLA offers a consistent vaccine component from lot to lot without the fluctuations in contaminants or activity that compromise natural-product adjuvants. Also provided are vaccines and pharmaceutical compositions that include GLA and one or more of an antigen, a Toll-like receptor (TLR) agonist, a co-adjuvant and a carrier such as a pharmaceutical carrier.
Inventors:
Reed, Stephen, Gee.
Carter, darrick
Carter, darrick
Application Number:
JP2016219466A
Publication Date:
August 30, 2017
Filing Date:
November 10, 2016
Export Citation:
Assignee:
Infectious Diseases Research Institute
International Classes:
A61K47/44; A61K9/08; A61K9/10; A61K9/107; A61K9/12; A61K9/127; A61K9/19; A61K35/76; A61K39/39; A61K47/02; A61K47/06; A61K47/10; A61K47/12; A61K47/14; A61K47/22; A61K47/24; A61K47/26; A61P37/04
Attorney, Agent or Firm:
Yusuke Hiraki
Satoshi Fujita
Eiichi Arai
Natsuo Tanaka
Satoshi Fujita
Eiichi Arai
Natsuo Tanaka
Previous Patent: Voice generating program
Next Patent: ANTICOAGULANT METHOD AND ANTICOAGUALNT POLYMER MATERIAL
Next Patent: ANTICOAGULANT METHOD AND ANTICOAGUALNT POLYMER MATERIAL