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Title:
NEIL3 PEPTIDE AND VACCINE COMPRISING SAME
Document Type and Number:
Japanese Patent JP2017132786
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide an isolated peptide or fragment thereof, which binds to HLA antigen and induces cytotoxic T lymphocytes (CTLs).SOLUTION: According to the present invention, an isolated peptide has abilities of binding to HLA antigen and inducing cytotoxic T lymphocytes (CTLs). The isolated peptide consists of a specific amino acid sequence or an immunologically active fragment thereof. The peptide consists of NEIL3 (Nei endonuclease VIII-like 3) or an immunologically active fragment thereof and may comprise the amino acid sequence, which binds to the HLA antigen, having the substitution, deletion, or addition of 1, 2, or several amino acid sequences.SELECTED DRAWING: None

Inventors:
TSUNODA TAKUYA
OSAWA RYUJI
YOSHIMURA SACHIKO
WATANABE TOMOHISA
NAKAMURA YUSUKE
FURUKAWA YOICHI
Application Number:
JP2017047970A
Publication Date:
August 03, 2017
Filing Date:
March 14, 2017
Export Citation:
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Assignee:
ONCOTHERAPY SCIENCE LTD
International Classes:
C07K14/47
Domestic Patent References:
JP2006052216A2006-02-23
Foreign References:
WO2004024766A12004-03-25
WO2008156827A22008-12-24
Other References:
PROTEIN EXPRESSION AND PURIFICATION, vol. 65, JPN6018008875, 2009, pages 160 - 164, ISSN: 0003881645
NCBI, JPN6018008861, 20 September 2005 (2005-09-20), pages 1439 - 2018, ISSN: 0003881646
NCBI, JPN6018008863, 13 April 2004 (2004-04-13), pages 825 - 2018, ISSN: 0003881647
NCBI, JPN6018008865, 1 September 2004 (2004-09-01), pages 756 - 2018, ISSN: 0003881648
PROTEIN EXPRESSION AND PURIFICATION, vol. 84, no. 1, JPN6018008873, 2012, pages 130 - 139, ISSN: 0003755627
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Hideki Kodera
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto