Title:
TOPK PEPTIDES AND VACCINES INCLUDING THE SAME
Document Type and Number:
Japanese Patent JP2017093442
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide peptides which have an ability to induce cytotoxic T lymphocytes (CTLs) and thus which are suitable for use in cancer immunotherapy.SOLUTION: Isolated epitope peptides derived from TOPK and immunogenic fragments thereof are nonapeptides or decapeptides containing a particular amino acid sequence, having an ability to induce cytotoxic T lymphocytes (CTLs). If a variant thereof in which one, two or some amino acids are substituted, deleted, inserted and/or added have an ability to induce CTL, a peptide encompasses both a peptide and such variant, and can form a complex with HLA antigens.SELECTED DRAWING: None
Inventors:
NAKAMURA YUSUKE
TSUNODA TAKUYA
OSAWA RYUJI
YOSHIMURA SACHIKO
WATANABE TOMOHISA
NAKAYAMA TAKESHI
TSUNODA TAKUYA
OSAWA RYUJI
YOSHIMURA SACHIKO
WATANABE TOMOHISA
NAKAYAMA TAKESHI
Application Number:
JP2016242382A
Publication Date:
June 01, 2017
Filing Date:
December 14, 2016
Export Citation:
Assignee:
ONCOTHERAPY SCIENCE LTD
International Classes:
C12N15/09; A61K39/00; A61K39/395; A61P35/00; A61P37/04; C07K7/06; C12N1/15; C12N1/19; C12N1/21; C12N5/0783; C12N5/0784; C12N5/10; C12Q1/02; C12Q1/68
Domestic Patent References:
| JP2010500003A | 2010-01-07 |
Foreign References:
| EP1972639A2 | 2008-09-24 | |||
| WO2011113819A2 | 2011-09-22 |
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto