METHOD AND KIT FOR EVALUATING VASCULAR LESIONS

Title:

METHOD AND KIT FOR EVALUATING VASCULAR LESIONS

Document Type and Number:

Japanese Patent JP2017049213

Kind Code:

A

Abstract:

PROBLEM TO BE SOLVED: To provide means of specifically and sensitively detecting vascular lesions including angiosarcomas.SOLUTION: A method of evaluating a vascular lesion in a subject involves measuring a biomarker expression level in a biological sample taken from the subject, and comparing the biomarker expression level with a reference value, where the biomarker is selected from a group comprising miR-214 and miR-126.SELECTED DRAWING: Figure 5

Inventors:

MURASE HIRONORI
AKAO YUKIHIRO
MARUO YUKITSUGU
MORI TAKASHI
SAKAI HIROKI

Application Number:

JP2015174896A

Publication Date:

March 09, 2017

Filing Date:

September 04, 2015

Export Citation:

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Assignee:

CCI CORP

International Classes:

G01N33/50; C12M1/34; C12Q1/68; G01N33/53

Domestic Patent References:

JP2014504881A	2014-02-27
JP2014082953A	2014-05-12
JP2010529966A	2010-09-02

Foreign References:

US20110086348A1	2011-04-14
US20090192111A1	2009-07-30

Other References:

HEISHIMA, K. ET AL.: "MicroRNA-214 Promotes Apoptosis in Canine Hemangiosarcoma by Targeting the COP1-p53 Axis", PLOS ONE, vol. Vol. 10, No. 9, e0137361, JPN6019013952, 3 September 2015 (2015-09-03), pages 1 - 19, ISSN: 0004019994
三浦直樹: "イヌ腫瘍の新規診断マーカーｍｉｃｒｏＲＮＡの探索に関する研究", 鹿児島大学リポジトリ, vol. http://hdl.handle.net/10232/14787, JPN6015046009, 31 May 2012 (2012-05-31), ISSN: 0004019995
SARVER, A. ET AL.: "S-MED: Sarcoma microRNA Expression Database", LABORATORY INVESTIGATION, vol. 90, JPN6019013953, 2010, pages 753 - 761, XP055092750, ISSN: 0004019996, DOI: 10.1038/labinvest.2010.53

Attorney, Agent or Firm:

Hatta International Patent Corporation

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