Title:
水溶性架橋剤
Document Type and Number:
Japanese Patent JP4602480
Kind Code:
B2
Abstract:
A chemical linking agent is formed of a di- or higher functional photoactivatable compound having at least one group that is charged to improve water solubility, and two or more photoreactive groups (preferably comprising an aryl ketone such as benzophenone) that allow use of the agent in aqueous systems. Charged groups include salts of organic acids such as sulfonate, phosphonate and carboxylate groups, onium groups such as quaternary ammonium, sulfonium and phosphonium groups, and protonated amines. A surface can be coated with a substance such as a synthetic polymer, carbohydrate, protein, lipid, nucleic acid, drug, vitamin, cofactor or dye by forming an aqueous solution of the linking agent and the substance, placing the solution in contact with the surface and activating the photoreactive groups of the linking agent to cross-link the substance to the surface.
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Inventors:
Swan, Dale Gee.
Amos, Richard A.
Everson, Terrence Pee.
Amos, Richard A.
Everson, Terrence Pee.
Application Number:
JP51760797A
Publication Date:
December 22, 2010
Filing Date:
October 31, 1996
Export Citation:
Assignee:
Thermodix, Incorporated
International Classes:
C07C225/16; C12N11/06; C07B61/00; C07C45/63; C07C309/14; C07D295/10; C07D295/112; C07D487/18; C07K17/06; C08J3/24; C09K3/00; G01N33/543
Domestic Patent References:
| JP7504926A | ||||
| JP8505839A | ||||
| JP62132880A |
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Yoichi Watanabe
Ryotaro Takei
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Yoichi Watanabe
Ryotaro Takei