Title:
病原体不活化のための脆い化合物
Document Type and Number:
Japanese Patent JP5244083
Kind Code:
B2
Abstract:
Compounds and methods for inactivating pathogens in materials are described, including compositions and methods for inactivating pathogens in biological materials such as red blood cell preparations and plasma. The compounds and methods may be used to treat materials intended for in vitro or in vivo use, such as clinical testing or transfusion. The compounds are designed to specifically bind to and react with nucleic acid, and then to degrade to form breakdown products. The degradation reaction is preferably slower than the reaction with nucleic acid.
Inventors:
David Cook
John merit
Irene Nerio
Henry Lapoport
Adonis Stasinopoulos
Susan Wollowitz
Jean Matejovik
John merit
Irene Nerio
Henry Lapoport
Adonis Stasinopoulos
Susan Wollowitz
Jean Matejovik
Application Number:
JP2009286996A
Publication Date:
July 24, 2013
Filing Date:
December 17, 2009
Export Citation:
Assignee:
Celus Corporation
International Classes:
C07D219/10; A01N1/00; A61K31/473; A61K35/14; A61L2/00; A61M1/02; A61P31/14; A61P31/18; B01J20/28; C07D405/12; C07D493/04; C07F9/64; C07F9/6561
Domestic Patent References:
| JP4551502B2 |
Foreign References:
| WO1996039818A1 |
Other References:
C. G. WERMUTH 編,長瀬博 監訳,最新 創薬化学 上巻,株式会社テクノミック発行,1998年 8月15日,第1版,第241-243頁,第255頁
Journal or Medicinal Chemistry,1990年,vol.33,1177-1186
Journal or Medicinal Chemistry,1990年,vol.33,1177-1186
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita