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Title:
1-[M-CARBOXAMIDO(HETERO)ARYL-METHYL]-HETEROCYCLYL-CARBOXAMIDE DERIVATIVES
Document Type and Number:
WIPO Patent Application WO/2013/190508
Kind Code:
A3
Abstract:
The present invention relates to 1-[m-carboxamido(hetero)aryl-methyl]-heterocycyl- carboxamide compounds of formula (I) wherein X, Ar1, R1, R2, R3, R4, R5a, R5b and p are as described in the description, to their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of formula (I), and especially to their use as CXCR7 receptor modulators.

Inventors:
FRETZ HEINZ (CH)
GUDE MARKUS (CH)
GUERRY PHILIPPE (CH)
KIMMERLIN THIERRY (CH)
LEHEMBRE FRANCOIS (CH)
PFEIFER THOMAS (CH)
VALDENAIRE ANJA (CH)
Application Number:
IB2013/055095
Publication Date:
March 13, 2014
Filing Date:
June 21, 2013
Export Citation:
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Assignee:
ACTELION PHARMACEUTICALS LTD (CH)
International Classes:
C07D401/06; A61K31/445; A61K31/4523; A61K31/4545; A61P29/00; A61P35/00; A61P37/00; C07D211/62
Domestic Patent References:
WO2008045564A22008-04-17
WO2009076404A12009-06-18
Foreign References:
Other References:
DATABASE REGISTRY [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 14 April 2011 (2011-04-14), XP002716814, retrieved from STN Database accession no. 1279884-55-7
DATABASE REGISTRY [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 1 May 2011 (2011-05-01), XP002716815, retrieved from STN Database accession no. 1287852-41-8
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