Title:
1-METHYLCARBAPENEM DERIVATIVES
Document Type and Number:
WIPO Patent Application WO/1997/041123
Kind Code:
A1
Abstract:
Constitution: 1-Methylcarbapenem compounds of general formula (I) and pharmacologically acceptable salts and derivatives thereof, wherein R1 is hydrogen or lower alkyl; R2 is hydrogen or lower alkyl; and R3 is hydrogen, lower alkyl, substituted lower alkyl, cycloalkyl or -C(=NH)R4 (wherein R4 is hydrogen, lower alkyl or amino). Effect: these compounds exhibit excellent antibacterial activity and are useful as preventive or therapeutic agents for infectious diseases.
Inventors:
KAWAMOTO ISAO (JP)
MORIMOTO MUNETSUGU (JP)
ISHIKAWA KATSUYA (JP)
KOJIMA KATSUHIKO (JP)
SHIMOJI YASUO (JP)
OHYA SATOSHI (JP)
MORIMOTO MUNETSUGU (JP)
ISHIKAWA KATSUYA (JP)
KOJIMA KATSUHIKO (JP)
SHIMOJI YASUO (JP)
OHYA SATOSHI (JP)
Application Number:
PCT/JP1997/001452
Publication Date:
November 06, 1997
Filing Date:
April 25, 1997
Export Citation:
Assignee:
SANKYO CO (JP)
KAWAMOTO ISAO (JP)
MORIMOTO MUNETSUGU (JP)
ISHIKAWA KATSUYA (JP)
KOJIMA KATSUHIKO (JP)
SHIMOJI YASUO (JP)
OHYA SATOSHI (JP)
KAWAMOTO ISAO (JP)
MORIMOTO MUNETSUGU (JP)
ISHIKAWA KATSUYA (JP)
KOJIMA KATSUHIKO (JP)
SHIMOJI YASUO (JP)
OHYA SATOSHI (JP)
International Classes:
A61K31/403; A61P31/04; C07D477/20; (IPC1-7): C07D487/04; A61K31/40
Foreign References:
JPH05310740A | 1993-11-22 | |||
JPH0848667A | 1996-02-20 | |||
JPH07228570A | 1995-08-29 | |||
JPH0748375A | 1995-02-21 | |||
JPH05339269A | 1993-12-21 |
Other References:
See also references of EP 0900797A4
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