Title:
10a-AZALIDE COMPOUND
Document Type and Number:
WIPO Patent Application WO/2007/091393
Kind Code:
A1
Abstract:
[PROBLEMS] To provide a compound which has a novel structure and is effective against an influenza bacterium and an erythromycin-resistant bacterium (e.g., an erythromycin-resistant pneumococcal or streptococcal bacterium), as well as a conventional erythromycin-sensitive bacterium. [MEANS FOR SOLVING PROBLEMS] Disclosed is a novel 10a-azalide compound represented by the formula (I), a pharmaceutically acceptable salt or solvate thereof, or an intermediate for the production of the compound or the salt or solvate. The compound has an excellent bactericidal activity against an influenza bacterium, an erythromycin-resistant pneumococcal bacterium and the like, and therefore can be used as a therapeutic agent for an infectious disease.
Inventors:
SUGIMOTO TOMOHIRO (JP)
YAMAMOTO KANAKO (JP)
MANAKA AKIRA (JP)
OGITA HARUHISA (JP)
KUROSAKA JUN (JP)
KAWAMURA MADOKA (JP)
KASHIMURA MASATO (JP)
SASAMOTO NAOKI (JP)
MIURA TOMOAKI (JP)
KANEMOTO KENICHI (JP)
OZAWA TOMOHIRO (JP)
CHIKAUCHI KEN (JP)
SHITARA EIKI (JP)
KUBOTA DAI (JP)
YAMAMOTO KANAKO (JP)
MANAKA AKIRA (JP)
OGITA HARUHISA (JP)
KUROSAKA JUN (JP)
KAWAMURA MADOKA (JP)
KASHIMURA MASATO (JP)
SASAMOTO NAOKI (JP)
MIURA TOMOAKI (JP)
KANEMOTO KENICHI (JP)
OZAWA TOMOHIRO (JP)
CHIKAUCHI KEN (JP)
SHITARA EIKI (JP)
KUBOTA DAI (JP)
Application Number:
PCT/JP2007/000068
Publication Date:
August 16, 2007
Filing Date:
February 07, 2007
Export Citation:
Assignee:
TAISHO PHARMACEUTICAL CO LTD (JP)
MEIJI SEIKA KAISHA (JP)
SUGIMOTO TOMOHIRO (JP)
YAMAMOTO KANAKO (JP)
MANAKA AKIRA (JP)
OGITA HARUHISA (JP)
KUROSAKA JUN (JP)
KAWAMURA MADOKA (JP)
KASHIMURA MASATO (JP)
SASAMOTO NAOKI (JP)
MIURA TOMOAKI (JP)
KANEMOTO KENICHI (JP)
OZAWA TOMOHIRO (JP)
CHIKAUCHI KEN (JP)
SHITARA EIKI (JP)
KUBOTA DAI (JP)
MEIJI SEIKA KAISHA (JP)
SUGIMOTO TOMOHIRO (JP)
YAMAMOTO KANAKO (JP)
MANAKA AKIRA (JP)
OGITA HARUHISA (JP)
KUROSAKA JUN (JP)
KAWAMURA MADOKA (JP)
KASHIMURA MASATO (JP)
SASAMOTO NAOKI (JP)
MIURA TOMOAKI (JP)
KANEMOTO KENICHI (JP)
OZAWA TOMOHIRO (JP)
CHIKAUCHI KEN (JP)
SHITARA EIKI (JP)
KUBOTA DAI (JP)
International Classes:
C07H17/00; C07H15/12; A61K31/7052; A61P31/04
Domestic Patent References:
| WO2005019238A1 | 2005-03-03 |
Other References:
LU W. ET AL.: "Chemoenzymatic synthesis of macrocyclic polyamines", TETRAHEDRON LETT., vol. 40, no. 27, 1999, pages 4965 - 4968, XP004169371
See also references of EP 1985620A4
See also references of EP 1985620A4
Attorney, Agent or Firm:
HIROSE, Takayuki (Chester Court Nihonbashi 1204 1-13, Nihonbashi Koami-cho, Chuo-k, Tokyo 16, JP)
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