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Title:
(11β,17α)-11-(4-(2-11C-ACETYL)PHENYL)-17,23-EPOXY- 19,24-DINORCHOLA-4,9,20-TRIEN-3-ONE
Document Type and Number:
WIPO Patent Application WO/2011/157443
Kind Code:
A8
Abstract:
The present invention relates to (11β,17α)-11-(4-(2-11C-acetyl)phenyl)-17,23- epoxy-19,24-dinorchola-4,9,20-trien-3-one, an 11C-labelled ORG 33628; a process for the preparation thereof, intermediates used in this process and the use of this compound as a PET tracer for the detection of breast cancer.

Inventors:
BRANDS, Franciscus Theodorus Leonardus (N.V. Organon, P.O. Box 20, BH Oss, NL-5340, NL)
HAMERSMA, Johannes, Antonius, Maria (N.V. Organon, P.O. Box 20, BH Oss, NL-5340, NL)
WIEGERINCK, Peter, Hermanus, Gerardus (N.V. Organon, P.O. Box 20, BH Oss, NL-5340, NL)
Application Number:
EP2011/003012
Publication Date:
August 02, 2012
Filing Date:
June 17, 2011
Export Citation:
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Assignee:
MSD OSS B.V. (Kloosterstraat 6, AB Oss, NL-5349, NL)
BRANDS, Franciscus Theodorus Leonardus (N.V. Organon, P.O. Box 20, BH Oss, NL-5340, NL)
HAMERSMA, Johannes, Antonius, Maria (N.V. Organon, P.O. Box 20, BH Oss, NL-5340, NL)
WIEGERINCK, Peter, Hermanus, Gerardus (N.V. Organon, P.O. Box 20, BH Oss, NL-5340, NL)
International Classes:
C07J21/00; A61K31/58; A61P5/36; G01N33/74
Attorney, Agent or Firm:
MERCK SHARP & DOHME LTD. (Attn: Patent Docket, Hertford RoadHoddesdon, Hertfordshire EN11 9BU, GB)
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