1,2-BENZISOSELENAZOL-3(2H)-ONE AND 1,2-BENZISOTHIAZOL-3(2H)-ONE DERIVATIVES AS BETA-LACTAM ANTIBIOTIC ADJUVANTS

Title:

1,2-BENZISOSELENAZOL-3(2H)-ONE AND 1,2-BENZISOTHIAZOL-3(2H)-ONE DERIVATIVES AS BETA-LACTAM ANTIBIOTIC ADJUVANTS

Document Type and Number:

WIPO Patent Application WO/2019/174279

Kind Code:

A1

Abstract:

Provided herein are compositions and methods useful in the treatment of beta-lactam antibiotic resistant bacteria.

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Inventors:

CHEN SHENG (CN)
CHAN KIN-FAI (CN)

Application Number:

PCT/CN2018/114268

Publication Date:

September 19, 2019

Filing Date:

November 07, 2018

Export Citation:

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Assignee:

UNIV HONG KONG POLYTECHNIC (CN)

International Classes:

A61K31/428; A61K31/43; A61P31/04; C07D275/04; C07D293/00

Domestic Patent References:

WO2017091737A1	2017-06-01
WO2011116355A2	2011-09-22

Foreign References:

US20140296310A1

2014-10-02

Other References:

JIN, W.B.: "Investigation of synergistic antimicrobial effects of the drug combinations of meropenem and 1, 2-benzisoselenazol-3(2H)-one derivatives on carbapenem-resistant Enterobacteriaceae producing NDM-1", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 155, 6 June 2018 (2018-06-06), pages 285 - 302, XP085431295, ISSN: 0223-5234, doi:10.1016/j.ejmech.2018.06.007

Attorney, Agent or Firm:

BEIJING PAT SF INTELLECTUAL PROPERTY AGENCY CO. LTD (CN)

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