1,4-BENZODIOXIN DERIVATIVES - NISSHIN FLOUR MILLING CO

Title:

1,4-BENZODIOXIN DERIVATIVES

Document Type and Number:

WIPO Patent Application WO/1996/035685

Kind Code:

A1

Abstract:

1,4-Benzodioxin derivatives represented by general formula (I), wherein A represents an aryl or cycloalkyl group; R1 and R2 represent each a hydrogen or halogen atom, or an alkyl, trifluoromethyl, alkoxy, aryl or aryloxy group, or R1 and R2 are combined together to represent a methylenedioxy group; R3 represents a hydrogen atom or an alkyl group; R4 represents a hydrogen atom or CO2R5; R5 represents a hydrogen atom or an alkyl group; and X is a group represented by general formula (II) or (III), wherein n is 1 or 2. The compounds are useful for a prophylactic or therapeutic agent for diabetes, hyperglycemia, and obesity.

Inventors:

TAKAHASHI TOSHIHIRO (JP)
INOMATA KOHEI (JP)
OSHIDA NORIO (JP)
KUBOTA NOBUTOSHI (JP)
HAMADA TAMIKO (JP)
IWATA NAOHITO (JP)

Application Number:

PCT/JP1996/001252

Publication Date:

November 14, 1996

Filing Date:

May 13, 1996

Export Citation:

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Assignee:

NISSHIN FLOUR MILLING CO (JP)
TAKAHASHI TOSHIHIRO (JP)
INOMATA KOHEI (JP)
OSHIDA NORIO (JP)
KUBOTA NOBUTOSHI (JP)
HAMADA TAMIKO (JP)
IWATA NAOHITO (JP)

International Classes:

C07D319/20; C07D405/06; C07D407/12; C07D413/06; (IPC1-7): C07D319/20; A61K31/335

Foreign References:

JPH07228543A	1995-08-29
JPH06293664A	1994-10-21
JPH05320153A	1993-12-03

Other References: